CompletedNot Applicable

Ondansetron Versus Domperidone for Treating Vomiting in Acute Gastroenteritis in Children

Pakistan300 participantsStarted 2020-07-01

Plain-language summary

Most of the trials conducted comparing ondansetron and domperidone have been conducted among children aged below 5 or 6 years of age while no study from Pakistan has compared efficacy of these antiemetic agents among children up to 12 years of age. The findings of present study will give valuable evidence about the effectiveness of these antiemetic agents to prevent vomiting among children suffering with acute gastroenteritis at a resource limited setting of South Punjab, Pakistan.

Who can participate

Age range1 Day – 12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children of both genders aged below 12 years of age having 3 or more non-bilious, non-bloody vomiting episodes within 24 hours and with suggestive signs and symptoms of Acte Gastroenteritis. Exclusion Criteria: * Children who took any kinds of antiemetic in the last 6 hours of presentation of emergency department. * Children having chronic liver disease, chronic kidney disease or congenital heart disease, neurological disorders, any kinds of malignancy, severe dehydration (requiring intravenous fluid replacement), severe acute malnutrition (weight-for-height below -3 standard deviation (SD) adopting WHO child growth protocols) or history known to allergy to antiemetics.

What they're measuring

Cessation of vomiting

Timeframe: 24 hours

Trial details

NCT IDNCT05076461

SponsorTehsil Headquarter Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2021-06-30

View on ClinicalTrials.gov More Vomiting in Infants and/or Children trials