UnknownNot Applicable

Water Drinking Test Study and Disc Hemorrhages in Normal Tension Glaucoma

20 participantsStarted 2021-10

Plain-language summary

Disc hemorrhages are a known risk factor for progression of glaucoma. A positive water drinking test is also associated with progression of primary open glaucoma. The purpose of this study is to determine if patients with normal tension glaucoma and disc hemorrhages have a positive water drinking test. Patients with normal tension glaucoma and a disc hemorrhage will be recruited to undergo a water drinking test prior to any change in their treatment.

Who can participate

Age range

18 Years – 90 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Clinical diagnosis of normal tension glaucoma by a fellowship trained glaucoma specialist, * Clinical diagnosis of a disc hemorrhage diagnosed by a fellowship trained glaucoma specialist, * Must be able to swallow water * Must be able to be positioned to allow accurate measurement of the Intraocular pressure with a slit lamp mounted Goldmann applanation tonometer * Must have a smooth corneal surface to allow for accurate Goldmann application tonometry measurement * Outpatient * A sufficient level of education to understand study procedures and be able to communicate with site personnel Exclusion Criteria: * History of refractive surgery, * Active ocular infection, * Pregnancy, * Cardiac or renal diseases, history of urinary retention, * Corneal abnormalities preventing reliable IOP measurements, * Previous trabeculectomy or glaucoma shunt surgery, * Previous laser iridotomy, * Cognitive impairment or language barrier preventing ability to provide an informed consent.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in baseline intraocular pressure(IOP) with water drinking test

Timeframe: The water drinking test takes 60 minutes, and the participant is then finished and can leave.

Trial details

NCT IDNCT05075369

SponsorUniversity of Manitoba

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-04

Contact for this trial

Lisa Gould, MD, FRCS

204-957-3252 lisa.gould@umanitoba.ca

View on ClinicalTrials.gov More Normal Tension Glaucoma trials