CompletedNot Applicable

Effect of rhBMP-2 or rhBMP-7 on Long Bone Fractures and Non-unions.

150 participantsStarted 2005-01

Plain-language summary

Delayed fracture healing continues to cause significant patient morbidity and economic burden to society. Biological stimulation of acute fractures and non-unions includes application of rhBMP-2 and rhBMP-7. However, BMP use continues to be a matter of controversy as literature shows scarce evidence for treatment effectiveness. The aim of this study is to compare acute fractures and non-unions in the long bones humerus, femur and tibia with and without BMP treatment of acute fractures. Furthermore, the investigators want to identify complications and risk factors on union-rate and time to union.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Long bone fracture or long bone non-union. * Signed informed consent, if required by IRB/EC Exclusion Criteria: Prisoner at date of inclusion

What they're measuring

Time to Union

Timeframe: 24 months

Union-rate

Timeframe: 24 months

Trial details

NCT IDNCT05065684

SponsorUniversity Hospital Muenster

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2012-01

View on ClinicalTrials.gov More Long Bone Non-union trials