Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments (NCT05065034) | Clinical Trial Compass
UnknownNot Applicable
Effects of Antibiotic Therapy on the Short and Long-term Results of Periodontitis Treatments
France200 participantsStarted 2021-09-29
Plain-language summary
Antibiotics are currently used in periodontology to specifically target the most pathogenic bacteria in subgingival biofilms and to improve treatments. The multiplicity of protocols / dosages tested and the variability of the results did not make it possible to reach an international consensus on antibiotic therapy and its cost / benefit ratio, in particular with regard to the significant side effects of taking antibiotics (resistance bacterial). The care environment as well as the clinical, biological and microbiological parameters can strongly influence the results in usual treatment.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Patient over 18 years old
* Patient treated for periodontitis between 01/01/2012 and 07/31/2021
* Patient whose medical and periodontal file contains all the elements necessary for data analysis
* Subject not having expressed, after information, his opposition to the reuse of his medical data for the purposes of this research.
Exclusion criteria:
* Patient who expressed his opposition to participating in the study
* Patient without periodontitis
* Patient smoking more than 10 cigarettes / day
* Patient presenting a dilapidated oral state (untreated caries, unrestored teeth), oral infectious foci whose management requires antibiotic treatment during the initial treatment
* Impossibility of giving the subject informed information
* Subject under safeguard of justice
* Subject under guardianship or guardianship
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
A retrospective study of the use of antibiotic therapy on the short and long-term results of periodontitis treatments
Timeframe: Files analysed retrospectively from January 01, 2012 to July 07, 2021 will be examined]