Realistic Computational Electrophysiology Simulations for the Targetted Treatment of Atrial Fibrillation

Inclusion Criteria: * Symptomatic paroxysmal atrial fibrillation or persistent atrial fibrillation diagnosed - within 24 months preceding the consent date. * Planned radiofrequency ablation for atrial fibrillation consisting of pulmonary vein isolation. * Able and willing to comply with study follow-up requirements * Able and willing to provide written informed consent Exclusion Criteria: * Any clinical contra-indication to ablation * Any disease limiting life expectancy to \< 1year * Contra-indication to MRI including renal dysfunction (eGFR\<30ml/min) * Potential participant currently pregnant or breast feeding * Prior ablation, cardiac surgery or presence of any prosthetic valves * Myocardial infarction or percutaneous coronary intervention within 3 months preceding consent date * Hypertrophic cardiomyopathy or other inherited cardiac condition * Presence / likely implant of any pacemaker, cardiac resynchronization therapy device or implantable defibrillator within 1 year * Enrolment in an existing interventional atrial fibrillation study which alters treatment or follow-up. * Use of amiodarone for any indication within 6 months prior to the planned ablation procedure * Use of any anti-arrhythmic drug for an arrhythmia indication other than atrial fibrillation * Prior documented cavotricuspid isthmus dependent right atrial flutter and planned cavotricuspid isthmus ablation to be performed at the time of atrial fibrillation ablation * Unable to understand verbal or writt…