CompletedNot Applicable

Angiotensin II Pathway and Postoperative Hypoxemia

China88 participantsStarted 2021-08-12

Plain-language summary

Acute type A aortic dissection is often accompanied by postoperative hypoxemia, the cause of which is not fully understood. Angiotensin II is an important component of the renin-angiotensin system (RAS), which has been suggested to be involved in the development of aortic dissection and pulmonary inflammation.The purpose of this study was to investigate the role and mechanism of angiotensin II pathway in postoperative hypoxemia after acute type A aortic dissection, and to provide reference for clinical application

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria: * patients undergoing surgery for acute type A aortic dissection * age between 18 to 80 Exclusion Criteria: * perioperative severe cardiac insufficiency * rejection of consent

What they're measuring

The Difference Concentrations of ANG II in Serum Between Patients With and Without Postoperative Hypoxemia.

Timeframe: Within 24 hours after surgery

Trial details

NCT IDNCT05055570

SponsorBeijing Anzhen Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-06-01

Results submitted2023-04-24

View on ClinicalTrials.gov More Aortic Dissection trials