Endoscopic Radiofrequency Ablation Versus Hybrid Argon Plasma Coagulation in the Treatment of Barrett's Esophagus

Inclusion Criteria: * Male or female subjects over 18 years * Histologically and endoscopically proven Barrett's esophagus requiring ablation therapy according to the current guidelines * General health status sufficient to perform an endoscopic procedure (ASA I-III) Exclusion Criteria: * Primary or secondary coagulopathy, with INR\>1.5 and/or platelet count of \<75,000. * Anticoagulation therapy (e.g. warfarin) for high-risk condition and unable to withhold the medication temporarily * Recent myocardial infraction or other significant cardiovascular event within 6 months prior to recruitment * Patients under long-term care and/or within nursing facilities (e.g. psychosocial disorders, mental retardation) * Any history of esophageal resection surgery * Esophageal varices