CompletedNot Applicable

Oxygen Reserve Index in One-Lung Ventilation During Elective Thoracic Operations

Turkey (Türkiye)50 participantsStarted 2020-03-01

Plain-language summary

The investigators' goal is to perform an observational cohort study investigating the use of oxygen reserve index (ORi) in patients undergoing elective thoracic surgery and one-lung ventilation (OLV). For this purpose, ORi values are recorded and compared to the other collected hemodynamical and oximeter parameters. The primary hemodynamic parameters include heart rate (HR) and blood pressure (BP), while; oximeter device-related parameters include peripheral oxygen saturation, perfusion index (PI), and pleth variability index (PVI). The investigators' secondary goal is to investigate relationships between these hemodynamical and oximeter parameters using statistical analysis methods.

Who can participate

Age range

22 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All patients at ages between 22 to 80 years old, * American Society of Anesthesiologists Physical Status (ASA-PS) risk groups of 1 to 3 * Elective thoracic surgery * Operational types of thoracic surgery include; either open lung resection with thoracotomy or video-assisted thoracic surgery (VATS) operative procedure along with general a anesthesia, DLT insertion, and OLV for all patients Exclusion Criteria: * Refusal to participate in a study, * History of severe asthma, * Severe renal and hepatic insufficiencies, * Pregnancy, * History of previous pulmonary resection, * Hemoglobinopathies.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Main Outcome Measure-(1)

Timeframe: Baseline time point after patient's arrival into operating room before anesthesia induction during elective thoracic operation

Main Outcome Measure-(2)

Timeframe: Preoxygenation time point before anesthesia induction during elective thoracic operation

Main Outcome Measure-(3)

Timeframe: Third time point during thoracic operation defined as; five minutes after tracheal intubation during two-lung ventilation in the supine position during elective thoracic operation

Main Outcome Measure-(4)

Timeframe: Fourth time point during thoracic operation defined as; 5 minutes after placing the patient in a lateral position with two-lung ventilation during elective thoracic operation

Main Outcome Measure-(5)

Timeframe: Fifth time point during thoracic operation defined as; at 1 minute after OLV placement during elective thoracic operation

Main Outcome Measure-(6)

Timeframe: Sixth time point during thoracic operation defined as; at 2 minute after OLV placement during elective thoracic operation.

Trial details

NCT IDNCT05050552

SponsorTrakya University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-07-15

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