CompletedNot Applicable

Oxygen Reserve Index in One-Lung Ventilation During Elective Thoracic Operations

Turkey (Türkiye)50 participantsStarted 2020-03-01

Plain-language summary

The investigators' goal is to perform an observational cohort study investigating the use of oxygen reserve index (ORi) in patients undergoing elective thoracic surgery and one-lung ventilation (OLV). For this purpose, ORi values are recorded and compared to the other collected hemodynamical and oximeter parameters. The primary hemodynamic parameters include heart rate (HR) and blood pressure (BP), while; oximeter device-related parameters include peripheral oxygen saturation, perfusion index (PI), and pleth variability index (PVI). The investigators' secondary goal is to investigate relationships between these hemodynamical and oximeter parameters using statistical analysis methods.

Who can participate

Age range22 Years – 80 Years

SexALL

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Inclusion Criteria: * All patients at ages between 22 to 80 years old, * American Society of Anesthesiologists Physical Status (ASA-PS) risk groups of 1 to 3 * Elective thoracic surgery * Operational types of thoracic surgery include; either open lung resection with thoracotomy or video-assisted thoracic surgery (VATS) operative procedure along with general a anesthesia, DLT insertion, and OLV for all patients Exclusion Criteria: * Refusal to participate in a study, * History of severe asthma, * Severe renal and hepatic insufficiencies, * Pregnancy, * History of previous pulmonary resection, * Hemoglobinopathies.

What they're measuring

Main Outcome Measure-(1)

Timeframe: Baseline time point after patient's arrival into operating room before anesthesia induction during elective thoracic operation

Main Outcome Measure-(2)

Timeframe: Preoxygenation time point before anesthesia induction during elective thoracic operation

Main Outcome Measure-(3)

Timeframe: Third time point during thoracic operation defined as; five minutes after tracheal intubation during two-lung ventilation in the supine position during elective thoracic operation

Main Outcome Measure-(4)

Timeframe: Fourth time point during thoracic operation defined as; 5 minutes after placing the patient in a lateral position with two-lung ventilation during elective thoracic operation

Main Outcome Measure-(5)

Timeframe: Fifth time point during thoracic operation defined as; at 1 minute after OLV placement during elective thoracic operation

Main Outcome Measure-(6)

Timeframe: Sixth time point during thoracic operation defined as; at 2 minute after OLV placement during elective thoracic operation.

Main Outcome Measure-(7)

Trial details

NCT IDNCT05050552

SponsorTrakya University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-07-15

View on ClinicalTrials.gov More One-Lung Ventilation trials