UnknownNot Applicable

Lavage With Super-Oxidized Solution for Secondary Peritonitis

Switzerland200 participantsStarted 2023-03-21

Plain-language summary

Secondary peritonitis is a frequent abdominal emergency that is still associated with a high morbidity and mortality rate due to surgical site infections (SSI) and sepsis. Early surgical source control is crucial to avoid sepsis and worse outcomes. The current randomized controlled trial aims to investigate the effect of peritoneal lavage with super-oxidized solution (SOS) on SSI and mortality in patients undergoing emergency abdominal surgery for secondary peritonitis. The investigators hypothesize that peritoneal lavage with SOS reduces the incidence of SSI and mortality in this patient population.

Who can participate

Age range19 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Secondary peritonitis due to suspected hollow viscus perforation, anastomotic insufficiency, and/or abdominal abscess (including patients with the named abdominal emergencies as a complication after elective surgery) * Scheduled emergency abdominal surgery by laparotomy with peritoneal lavage * Age over 18 years * Written informed consent Exclusion Criteria * Pregnancy (will be ruled out using beta-hCG testing in women of childbearing potential) * Patients with primary or tertiary peritonitis

What they're measuring

Composite endpoint of surgical site infection and mortality

Timeframe: 30 days

Trial details

NCT IDNCT05050253

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-04

Contact for this trial

Tobias Haltmeier, MD

+41 31 664 03 04 tobias.haltmeier@insel.ch

View on ClinicalTrials.gov More Peritonitis trials