Active — Not RecruitingNot Applicable

Comparing Two Surveillance Approaches for People Who Have Received Treatment for HPV-associated Head and Neck Cancer and Show No Signs of Disease

United States40 participantsStarted 2021-09-01

Plain-language summary

The purpose of this study is to compare standard surveillance with telemedicine surveillance (tele-surveillance) and find out which surveillance approach is best for people with HPV-associated head and neck cancer who have no evidence of disease after treatment. The researches will look at how the two approaches affect participants' quality of life, health outcomes, and expenses (for example, costs of routine visits and procedures). They will also determine doctors' and patients' satisfaction with tele-surveillance.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 18 * ECOG 0-3 * Pathologically (histologically or cytologically) diagnosis of HPV associated squamous cell carcinoma of the oropharynx (tonsil, base of tongue, or oropharyngeal walls) * No evidence of disease on post-treatment PET/CT within 9 months of completing radiation therapy. No evidence of disease is a consensus determination by the patient's radiation, medical, and surgical oncologist. If the first PET/CT is equivocal, then a second PET/CT can be obtained within 9 months of completing radiation therapy. * Post-treatment diagnostic imaging with either CT or MRI (recommended but not required) * Able to speak and read English fluently * Able to provide informed consent Exclusion Criteria: * Patients on clinical trials related to head and neck cancer that have protocol defined follow up activities * Incomplete response or recurrent disease on post-treatment PET/CT * Completion of radiation and chemotherapy more than 9 months ago

What they're measuring

Progression-Free Survival (PFS)

Timeframe: 2 years

Trial details

NCT IDNCT05048459

SponsorMemorial Sloan Kettering Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09