UnknownNot Applicable

Dietary Salt During Pregnancy and Maternal Vascular Function

Croatia80 participantsStarted 2021-09-01

Plain-language summary

The main goal of this study is to investigate the association of dietary salt intake during pregnancy with systemic micro- and macrovascular reactivity and uteroplacental vascular function of the mother, and to examine the potential impact of elevated oxidative stress on this association. Also, the aim is to investigate whether there is an association between excessive salt intake during pregnancy and the outcome of pregnancy.

Who can participate

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * healthy pregnant women in the third trimester of pregnancy (37-38 weeks of pregnancy) Exclusion Criteria: * smoking * prenatal hypertension * thrombophilia * low molecular weight heparin use * coronary heart disease * preconception diabetes * gestational diabetes * renal impairment * cerebrovascular and peripheral artery disease * any other preconception disease that could affect vascular and endothelial function

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Since this study is specifically looking at how dietary salt affects blood vessel function during pregnancy — including the placenta — could reducing my salt intake actually have a meaningful impact on my vascular health while I'm pregnant?
2This trial is listed with an unknown recruitment status, so is it still actively enrolling, and would it even be possible for me to participate at this stage of my pregnancy?
3The study measures three different types of vascular function — microvascular, macrovascular, and uteroplacental — what do those terms mean for my and my baby's health, and are any of them relevant to risks I already have?
4Since this appears to be a non-drug lifestyle study rather than a medication trial, are there any risks to me or my baby from changing my salt intake as part of a research protocol during pregnancy?
5Before considering something like this, would you recommend I simply follow standard dietary guidelines on salt during pregnancy first, and how does that compare to what this trial is asking participants to do?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Maternal systemic microvascular function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)

Maternal systemic macrovascular function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)

Maternal uteroplacental function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)

Trial details

NCT IDNCT05048225

SponsorJosip Juraj Strossmayer University of Osijek

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-12-31

Contact for this trial

Martina Vulin, MD

+38531512300 martina.vulin@gmail.com

View on ClinicalTrials.gov More Salt; Excess trials

Plain-language summary

Who can participate

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Maternal systemic microvascular function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)

Maternal systemic macrovascular function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)

Maternal uteroplacental function

Timeframe: at one time point in the third trimester of pregnancy (37-38 weeks of pregnancy)