Active — Not RecruitingNot Applicable

Effectiveness of Percutaneous Pulley Release With Infiltration, Versus Infiltration Alone in Trigger Finders

France50 participantsStarted 2022-05-31

Plain-language summary

Trigger finger is a mechanical problem characterized by pain and catching of digit in flexion. Histological changes of A1 pulley and synovial proliferation have been identified as factors that prompt trigger finger The first-line treatment of trigger finger is conservative with splinting and corticosteroid injection. If the first infiltration fails, either a second infiltration or surgical sectioning of the pulley is proposed. Surgery can be performed by several techniques (open section, percutaneous section with palpatory guidance, or under ultrasound guidance). Percutaneous A1 pulley release under ultrasound guidance consists of cutting the A1 pulley by a percutaneous insertion with small needle under local anaesthesia. The hypothesis of the study is that percutaneous A1 pulley release under ultrasound guidance followed by a corticosteroid injection would be more effective than a second corticosteroid injection alone on complete resolution of the trigger finger symptoms

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient ≥ 18 years old, * Presence of a trigger finger (thumb or long fingers) to be treated * Quinnell score \>1 * Episode of trigger characterized on questioning or clinical examination * Failure of a first corticosteroid infiltration \> 3 months before inclusion * First infiltration within 15 months of inclusion * Thickening A1 pulley on ultrasound ≥ 0.5 mm * Patient who has the capacity to understand the protocol and has given consent to participate in the research, * Patient with social security coverage Exclusion Criteria: * Presence of several symptomatic fingers requiring treatment by ultrasound-guided section of the pulley * Patient who are pregnant, breastfeeding, or who have the potential to become pregnant without effective contraception at the time of inclusion * Known allergy to corticoid (Hydrocortancyl®) including its excipients ((benzyl alcohol, sodium carmellose, sodium chloride, polysorbate 80) * Known allergies to lidocaine * Ongoing anticoagulant treatments (AVK, New Oral Anti-Coagulants) * Local or general infection, or suspicion of infection * Live vaccines * Evolving viruses (hepatitis, herpes, varicella, shingles) * Severe or uncontrolled hypertension * Unbalanced diabetes * Underlying progressive cardiovascular disease * Hemodialysis patients * Prosthesis on the finger to be treated * Echographic tendon fissure * Inflammatory disease (rheumatoid arthritis, spondyloarthritis, connective tissue diseases, etc.) with tenosynoviti…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1This trial compares a percutaneous pulley release procedure done with ultrasound guidance plus a corticosteroid injection versus a corticosteroid injection alone — which of those two approaches does my doctor currently think is more likely to fully resolve my trigger finger symptoms based on what's known so far?
2Since this trial is listed as 'active, not recruiting,' it sounds like enrollment is closed — does that mean results might be available soon, and should we wait to see those findings before deciding on my treatment plan?
3The trial involves a percutaneous pulley release, which is a minimally invasive procedure done through the skin — how does that compare in terms of risks and recovery time to just getting a corticosteroid injection on its own, which is already a standard treatment?
4This study is listed as Phase NA, meaning it may not follow the traditional drug trial phases — what does that mean for how confident my doctor can be about the safety and effectiveness of the percutaneous pulley release approach right now?
5Given that this trial is specifically studying complete resolution of trigger finger symptoms, is a corticosteroid injection alone something my doctor would recommend trying first before considering a procedure like pulley release, or does my specific situation suggest moving more quickly to an interventional option?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Effectiveness of pulley section with ultrasound guidance combined with corticosteroid infiltration versus corticosteroid alone on complete resolution of trigger finger's symptoms

Timeframe: 1 year postoperatively

Trial details

NCT IDNCT05045157

SponsorCentre Hospitalier Departemental Vendee

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-31

View on ClinicalTrials.gov More Trigger Finger trials