Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults (NCT05043454) | Clinical Trial Compass
CompletedNot Applicable
Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults
United States11 participantsStarted 2021-10-01
Plain-language summary
The investigator aims to assess the extent to which a brief exercise intervention improves systemic growth factor concentrations, reverses loss of systemic vascular networks and hypertension, and by extension, improves neurocognition. To test the investigator's hypothesis that increased cardiovascular fitness will correlate with improved vascular density, the investigator proposes the innovative use of retinal density scans.
Who can participate
Age range
55 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* adults between 55-75 years of age
* essential hypertension (as determined by referring physicians)
* engages in less than 150 minutes of moderate intensity exercise/week (as determined by CHAMPS Questionnaire)
* physically able to exercise
* access to an upright cycle ergometer at home or via gym access
* access to smart device (iOS or Android phone or tablet with ability to install and use Polar Beat and Polar FlowTM applications).
Exclusion Criteria:
* diagnosis of dementia
* resting systolic blood pressure \<120, or \>180 mm Hg
* disease or condition that would preclude exercise
* untreated depression or anxiety disorders
* severe respiratory disease
* disease of the eye
* refractive error \> 6 diopters or +6 diopters (as assessed by 1st retinal scan).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.