Active — Not RecruitingNot Applicable

Swedish Microinvasive Glaucoma Surgery Study (SMIGS)

Sweden120 participantsStarted 2021-09-16

Plain-language summary

The purpose of the study is to investigate the efficacy of Cataract Surgery as stand-alone compared to Cataract Surgery in combination with Kahook Dual Blade Glide goniotomy (KDB) or iStent Inject W Trabecular Microbypass Stent (Istent) in eyes with Open-angle glaucoma.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Only one eye per participant * Clinically significant cataract * Glaucoma or intraocular hypertension treated with one to four medications and no need for filtering glaucoma surgery at the time of study enrollment. * Open chamber angle with Schaffer grading three to four in at least two quadrants Exclusion Criteria: * Previous glaucoma surgery, including cyclodestructive procedures. * Selective Laser Trabeculoplasty (SLT) within 90 days prior to planned surgery. * Exudative age-related macular degeneration, proliferative diabetic retinopathy, clinically significant corneal dystrophy, other eye disease that affect intraocular eye pressure or visual field. * Unable to participate and make written consent due to another medical condition.

What they're measuring

Change in the number of intraocular pressure lowering medications compared to baseline

Timeframe: 12 to 24 months

Number of participants with ≥20 percent intraocular pressure reduction or reduction with ≥1 medication compared to baseline

Timeframe: 12 to 24 months

Trial details

NCT IDNCT05035394

SponsorUmeå University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09

View on ClinicalTrials.gov More Open Angle Glaucoma trials