TerminatedNot Applicable

Exercise Preconditioning in Ovarian Cancer

Stopped: Accrual not meeting pre-specified numbers.

United States8 participantsStarted 2021-10-21

Plain-language summary

The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, peripheral neuropathy, and quality of life.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 years or over * Presumed diagnosis of ovarian cancer and a planned chemotherapy regimen of a taxane and carboplatin with or without VEGF inhibition * Physician clearance for exercise training Exclusion Criteria: * Any patient unable/unwilling to cooperate with all study protocols * Cancer recurrence * Previous treatment with chemotherapy in the last 5-years * Medical/orthopedic co-morbidities that preclude exercise training * Significant heart, liver, kidney, blood, or respiratory disease precluding exercise participation * Peripheral vascular disease * Acute infectious disease or history of chronic infections

What they're measuring

VO2 Peak

Timeframe: 22 weeks

Trial details

NCT IDNCT05029154

SponsorUniversity of Virginia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-04

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