Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Med… (NCT05021809) | Clinical Trial Compass
UnknownPhase 4
Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication .
Egypt60 participantsStarted 2021-07-25
Plain-language summary
Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of post-treatment symptoms. Calcium hydroxide has a pain-controlling effect at different times when compared to non-intracanal medication .
Aim:
The aim of the study to compare between postoperative pain after using two formulations of calcium hydroxide intracanal medication with and without iodoform .
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* .single-rooted teeth with pulpal necrosis and symptomatic apical periodontitis with visible radiographic disturbance of periapical lamina dura. The diagnosis of pulp necrosis was confirmed by negative response to cold test, electric pulp tester and clinically by absence of blood upon access cavity .
* Clinical signs of apical periodontitis.
* Teeth with sufficient coronal tooth structure for adequate rubber dam isolation were selected .
* Patients who are over 18 years old .
Exclusion Criteria:
* Presence of open apices
* Presence of non-restorable teeth
* Presence of large carious lesions approaching the root.
* Presence of calcification or resorption .
* Patients who had received antibiotics during the last 3 months .
* Teeth with periodontal probing depth \> 4 ml.
* Teeth with previous root canal treatment .
* Teeth with fluctuant facial swelling .
* Pregnant females.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 4 hours .
2
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 6 hours.
3
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 12 hours .
4
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 24 hours .
5
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 48 hours .
6
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded at 72 hours .
7
Measuring the severity of postoperative pain in both groups.
Timeframe: The pain score will be recorded after one week.