CompletedNot Applicable

TyG Index Levels in Klinefelter Syndrome

60 participantsStarted 2013-02-10

Plain-language summary

It is well known that the frequency of cardiometabolic diseases are increased in patients with Klinefelter Syndrome. The triglyceride-glucose index (TyG index) is a simple surrogate marker of insulin resistance and is also associated with various cardiometabolic diseases. The aim of this study to investigate the TyG index levels and its relationship with insulin resistance and endothelial dysfunction in patients with KS.

Who can participate

Age range18 Years – 28 Years

SexMALE

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Inclusion Criteria: * Patients with a verified Klifelter Syndrome karyotype (all subjects included were 47, XXY) and who were not previously given testosterone replacement. Exclusion Criteria: * age \<18 years, * acute infection, malignancy, any visceral organ dysfunction, nutritional derangements, clinical history of cardiovascular disease, cerebrovascular disease, drug use such as antidiabetic or lipid-lowering medications, or those lacking complete clinical data.

What they're measuring

Cardiometabolic risk

Timeframe: 1 day

Trial details

NCT IDNCT05014997

SponsorGulhane School of Medicine

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2014-10-01

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