WithdrawnNot Applicable

Combined Dexmedetomidine and Glycopyrrolate Therapy

Stopped: We could not get the IRB approval

0Started 2021-09-01

Plain-language summary

Catheter-related bladder discomfort after transurethral resection of bladder tumor is frequent because of indwelling urinary catheter for irrigation. The mechanism of the catheter-related bladder discomfort is similar to that of overactive bladder, in which muscarinic acetylcholine receptors are stimulated. The catheter-related bladder discomfort is a well known predisposing factor for emergence delirium after general anesthesia. In this study, we aimed to compare the incidence of catheter-related bladder discomfort between dexmedetomidine only therapy and combind dexmedetomidine and glycopyrrolate therapy.

Who can participate

Age range19 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologists physical status I and II * elective transurethral resection of bladder tumor under general anesthesia Exclusion Criteria: * arrhythmia * bladder outflow obstruction * overacitve bladder * end stage renal disease * neurogenic bladder * morbid obesity * psychiatric disorder

What they're measuring

The incidence of catheter-related bladder discomfort

Timeframe: 0 minute after entering the post-anesthetic care unit

Trial details

NCT IDNCT05013320

SponsorKangbuk Samsung Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-31

View on ClinicalTrials.gov More Bladder Irritable trials