Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule

Inclusion Criteria: * Patient is older than 18 years, is not a surgical candidate or refuses to have surgery * Patient is medically fit to undergo local anesthesia with or without conscious sedation * Patient is able to understand and give consent to participation in the study * Presence of compression symptoms or cosmetic concerns for which patient request treatment of the benign thyroid nodule * Solitary thyroid nodule or dominating nodule that is well-defined in multinodular goiter * Benign nodule is \>= 2 cm in the largest dimension, and has either solid, or predominantly solid composition (\>= 70% volume) without large calcification. Nodule is confirmed as benign (Bethesda II) on at least 2 ultrasound guided fine needle aspirations (FNA) or core needle biopsy (CNB) or a single benign diagnosis of FNA or CNB when the nodule has benign ultrasound features (American College of Radiology \[ACR\] Thyroid Imaging Reporting \& Data System \[TI-RAD\] TR 1-3, American Thyroid Association \[ATA\] very low suspicion) within 6 months of planned RFA * Indeterminate thyroid nodule (atypical cells of undetermined significance \[ACUS\], follicular neoplasm), papillary thyroid carcinoma (PTC) without metastasis or locally recurrent thyroid cancer \< 2 cm in the largest dimension. Nodule cytology is confirmed on a single FNA or CNB when the nodule has concordant ultrasound features (ACR TI-RAD TR 4-5, ATA intermediate-high suspicion) within 6 months of planned RFA * Entirety of the selec…