UnknownNot Applicable

Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?

United States200 participantsStarted 2020-08-06

Plain-language summary

The purpose of this study is to determine whether the addition of the superficial parasternal intercostal plane (SPIP) block alone (30cc of 0.25% bupivacaine) or plus Magnesium (200mg of magnesium sulfate) or plus Magnesium + Buprenorphine (300mcg) as adjuvants can improve post-operative pain in patients undergoing cardiothoracic surgery, specifically, coronary artery bypass grafting (CABG)

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing primary coronary artery bypass grafting Exclusion Criteria: * Patients with significant genetic or acquired clotting/bleeding disorders (hemophilia, DIC, etc.) * Patients with significant platelet dysfunction * Infection at site for regional anesthesia * Allergy to local anesthetics * Severe aortic stenosis * Severe mitral stenosis * Sepsis

What they're measuring

Post-operative total opioid consumption (oral morphine equivalents)

Timeframe: 24 hours after the surgery

Visual analog scale (VAS) pain scores

Timeframe: 6 hours after surgery

Visual analog scale (VAS) pain scores

Timeframe: 12 hours after surgery

Visual analog pain (VAS) scores

Timeframe: 24 hours after surgery

Length of hospital stay (LOS)

Timeframe: Up to 1 month

Trial details

NCT IDNCT05003765

SponsorWayne State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-05-01

Contact for this trial

Sandeep H Krishnan, MD

(248) 858-6068 sakrishna@med.wayne.edu

View on ClinicalTrials.gov More Post-operative Pain Management trials