RecruitingNot Applicable

Multi-omics Research of Idopathic Normal Pressure Hydrocephalus (iNPH)

China40 participantsStarted 2020-09-15

Plain-language summary

The research is designed to study the prognostic factors of ventriculoperitoneal (VP) shunt for iNPH by multi-omics research

Who can participate

Age range60 Years – 90 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥ 60 years; * Diagnosis of iNPH based on clinical assessment * Participant is able to give written informed consent Exclusion Criteria: * Combining AD and Parkinson's disease and other nervous system diseases * Participant is not medically available for shunt surgery * Secondary NPH

What they're measuring

Proteomic pattern of CSF in iNPH patients

Timeframe: Before surgery in lumbar CSF

Proteomic pattern changes of CSF in iNPH patients after VP shunt

Timeframe: Change from Baseline (ventricular CSF) at 6 months after VP shunt

Trial details

NCT IDNCT04998175

SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-30

Contact for this trial

Junming Zhu, M.D.

86-13968055768 dr.zhujunming@zju.edu.cn

View on ClinicalTrials.gov More Idiopathic Normal Pressure Hydrocephalus trials