UnknownPhase 4

Ketofol Versus Propofol in Urgent ERCP for Acute Cholangitis

Egypt100 participantsStarted 2020-07-01

Plain-language summary

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a lengthy and uncomfortable procedure that requires adequate sedation. Propofol is the commonly used sedative during ERCP. However, dose dependent cardiac and respiratory depression may occur. Hypotension usually occurs in severe cholangitis which necessitate the use of alternative sedative. The aim is to study the efficacy and safety of ketofol as a sedative during urgent ERCP for severe cholangitis.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Severe acute cholangitis of either sex * Aged between 21-70 years * Undergoing urgent therapeutic ERCP for severe cholangitis with American Society of Anaesthesiologist (ASA) Grade II - III. Exclusion Criteria: * Patients who had ASA physical status Grade VI, * Baseline SpO2 \<90%, * Patients who had difficulty in communication, * Patients allergic to the studied medications, * Morbidly obese patients, * Patients with chronic obstructive pulmonary disease, * Complicated airway, * Pregnant patients.

What they're measuring

Efficacy of ketofol in sedation

Timeframe: 24 hours

Trial details

NCT IDNCT04997967

SponsorAssiut University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-08

Contact for this trial

Haidi Ramadan, Phd

+201028186710 haidikaram@aun.edu.eg

View on ClinicalTrials.gov More Conscious Sedation Failure During Procedure trials