Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

Inclusion Criteria: * Adult patients ≥ 18 years of age with definite CP undergoing decompressive invasive treatments (endoscopic therapy or surgery) to relieve main pancreatic duct obstruction due to stones and/or stricture for management of pain. * Endoscopic therapy: Endoscopic Retrograde Cholangiopancreatography (ERCP) with pancreatic duct stone removal, stent placement, and/or stricture dilation, ± intraductal lithotripsy or Extracorporeal Shock Wave Lithotripsy (ESWL). * Surgery: drainage procedures (Frey and Puestow operations) Exclusion Criteria: * Patients with chronic pain from conditions other than CP * Patients \< 18 years of age * Patients who have had endoscopic therapy within the past 12 months * Patients who have undergone prior pancreatic surgery * Patients who have resective surgical procedure planned (eg. Whipple procedure, Total Pancreatectomy) * Patients with peripheral sensory deficits * Patients with known pregnancy at the time of study screening\*\* * Note: Women who become pregnant during the course of the study can no longer participate in P-QST testing.