UnknownNot Applicable

Low-field Magnetic Resonance Imaging of Pediatric COVID-19

Germany68 participantsStarted 2021-08-09

Plain-language summary

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a new coronavirus and identified causative agent of COVID-19 disease. They predominantly cause mild colds but can sometimes cause severe pneumonia. The long-term consequences are still largely unexplained and misunderstood, especially in children and adolescents. The aim of this study is to assess the frequency of pulmonary skeletal changes in pediatric and adolescent patients using low-field magnetic resonance imaging (LF-MRI) in the setting of proven past SARS-CoV-2 infection.

Who can participate

Age range5 Years – 18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Covid-19 group Inclusion Criteria: * (Past) Positive SARS-CoV-2 Infection (PCR proven) * Age 5 to \<18 years Exclusion Criteria: * Acute SARS-CoV-2 Infection and Isolation * Quarantine * Pregnancy * Critical Illness * No consent to LF\_MRI * General contraindications for LF-MRI, such as electrical implants, pace makers, perfusion pumps) Healthy controls Inclusion Criteria: \- Age 5 to \<18 years Exclusion Criteria: * (Past) Positive SARS-CoV-2 Infection (PCR or antigen test proven) * Suspect for lung disease * Acute respiratory infection/symptomatic * Acute SARS-CoV-2 Infection and Isolation * Quarantine * Pregnancy * Critical Illness * No consent to LF\_MRI * General contraindications for LF-MRI, such as electrical implants, pace makers, perfusion pumps)

What they're measuring

Low-field magnetic resonance imaging

Timeframe: Single time point (1 day)

Trial details

NCT IDNCT04990531

SponsorUniversity of Erlangen-Nürnberg Medical School

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-29

Contact for this trial

Alexandra Wagner, MD

+49913185 alexandra.l.wagner@uk-erlangen.de