Low-field Magnetic Resonance Imaging of Pediatric COVID-19 (NCT04990531) | Clinical Trial Compass
UnknownNot Applicable
Low-field Magnetic Resonance Imaging of Pediatric COVID-19
Germany68 participantsStarted 2021-08-09
Plain-language summary
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus type 2) is a new coronavirus and identified causative agent of COVID-19 disease. They predominantly cause mild colds but can sometimes cause severe pneumonia. The long-term consequences are still largely unexplained and misunderstood, especially in children and adolescents. The aim of this study is to assess the frequency of pulmonary skeletal changes in pediatric and adolescent patients using low-field magnetic resonance imaging (LF-MRI) in the setting of proven past SARS-CoV-2 infection.
Who can participate
Age range
5 Years – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Covid-19 group
Inclusion Criteria:
* (Past) Positive SARS-CoV-2 Infection (PCR proven)
* Age 5 to \<18 years
Exclusion Criteria:
* Acute SARS-CoV-2 Infection and Isolation
* Quarantine
* Pregnancy
* Critical Illness
* No consent to LF\_MRI
* General contraindications for LF-MRI, such as electrical implants, pace makers, perfusion pumps)
Healthy controls
Inclusion Criteria:
\- Age 5 to \<18 years
Exclusion Criteria:
* (Past) Positive SARS-CoV-2 Infection (PCR or antigen test proven)
* Suspect for lung disease
* Acute respiratory infection/symptomatic
* Acute SARS-CoV-2 Infection and Isolation
* Quarantine
* Pregnancy
* Critical Illness
* No consent to LF\_MRI
* General contraindications for LF-MRI, such as electrical implants, pace makers, perfusion pumps)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Low-field magnetic resonance imaging
Timeframe: Single time point (1 day)
Trial details
NCT IDNCT04990531
SponsorUniversity of Erlangen-Nürnberg Medical School