The Effect of 12-week Dietary Intake of Food Supplements Containing Collagen on Dermis Density and Other Skin Parameters

Inclusion criteria: * Caucasian female volunteers aged between 40 and 65 years at the time of the signature of Informed consent form (ICF), * Signed Informed consent form (ICF), * Fitzpatrick skin phototypes I-IV, * Signs of skin aging, * In good general health condition, * Body mass index (BMI) \< 35 * Willingness to avoid a consumption of any food supplements containing methylsulfonylmethane (MSM), antioxidants, collagen and other protein-based food supplements during the study, * Willingness to follow all study procedures and keeping a diary during the study (to follow their compliance and palatability). * Willingness to maintain their living habits and to not begin or change any estrogen or progesterone therapies, * Willingness to avoid shaving/depilation of their arms during the study, * Willingness not to change cosmetic treatment routine during the study, * Willingness to avoid rejuvenation treatments during the study. Exclusion criteria: * Pregnancy or breastfeeding, * Known or suspected allergy to any ingredient of the tested products, * Changes in dietary habits and dietary supplementation in the last three months prior to inclusion, * Regular use of food supplements containing MSM, antioxidants, collagen or other protein-based food supplements in the last three months prior to inclusion, * Veganism, * Changes in cosmetic facial and body care routine in the last month prior to inclusion, * Diagnosed and uncontrolled/unregulated disease, * Any clinically significa…