WithdrawnNot Applicable

Eccentric Resistance Training With Blood Flow Restriction on Muscle Function

Stopped: A key faculty at our college who was helping with the project left the college.

United States0Started 2024-03-30

Plain-language summary

The study will determine the effects of adding blood flow restriction to eccentric training to assess whether this increases the improvements of muscle strength and size.

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-30 years of age * currently engaged in some form of resistance training between 1-3 times per week * must have been training aerobically, but no more than 3 hours a week for the past six months Exclusion Criteria: * Must not have had any surgery of the lower limbs within the past 1 year period * Must not have any neuromuscular disorder (e.g., Muscular dystrophy etc.) * \< 76 inches tall (in order to fit on the training machine) * Maximal strength of \< 725 lbs for the eccentric training device * If any of the subjects are pregnant or plan to be pregnant in the duration of the protocol. For those randomized to the BFR group, if any of the subject's thighs are too large for the BFR cuffs (greater than 68 cm).

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Eccentron maximal muscle strength

Timeframe: 7 weeks

Local muscle hypertrophy

Timeframe: 7 weeks

Muscle mass

Timeframe: 7 weeks

Muscle function

Timeframe: 7 weeks

Trial details

NCT IDNCT04977804

SponsorUtah State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

View on ClinicalTrials.gov More Blood Flow Restriction trials

Who can participate

Age range

18 Years – 30 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.