WithdrawnPhase 4

Dextenza vs Prednisolone Acetate After Cataract Surgery for Patients With Diabetes

Stopped: PI chose to go a different direction due to strict timeline for data collection.

0Started 2021-08-31

Plain-language summary

This study aims to compare the effectiveness of Dextenza vs standard of care prednisolone taper after cataract surgery in diabetic patients with regards to controlling post-op inflammation at post-op days 7, 14, and 30.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with diagnosed diabetes * Patients must be undergoing cataract surgery in each eye * Patients must have no worse than moderate nonproliferative diabetic retinopathy Exclusion Criteria: * Patients must not have any history of documented macular edema on OCT * Patients must not have any macular edema on pre-op OCT * Patients must not have any history of uveitis * Patients must not have severe nonproliferative or proliferative diabetic retinopathy * Patients with operative complications will be excluded from this study * Patients with any active corneal disease, infectious or rheumatologic, will be excluded * Patients must not be pregnant

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Optical Coherence Tomography (OCT)

Timeframe: 7 days

Optical Coherence Tomography (OCT)

Timeframe: 14 days

Optical Coherence Tomography (OCT)

Timeframe: 30 days

Trial details

NCT IDNCT04977427

SponsorBaylor Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-12-20

View on ClinicalTrials.gov More Cataract Diabetic trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.