CompletedNot Applicable

A Telerehabilitation Program for SCI

United States20 participantsStarted 2021-07-01

Plain-language summary

This study evaluates a remotely supervised, home-based therapeutic program to improve upper-limb voluntary movement in adults with tetraplegia caused by incomplete spinal cord injury (iSCI).

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. diagnosis of a chronic incomplete cervical lesion as defined by the American Spinal Injury Association Impairment scale classification and at least for 6 months post-injury;
✓. upper-extremity weakness associated with tetraplegia with minimal residual thumb and index; finger movement sufficient to grip small objects such as marble;
✓. no brain injury;
✓. no planned alteration in upper-extremity therapy or medication for muscle tone during the course of the study;
✓. no contradiction to tDCS;
✓. access to internet at home.

Exclusion criteria

✕. prior history of seizure;
✕. chronic use of neuroactive medication (e.g., neurostimulants, anticonvulsants, or antidepressants);
✕. any joint contracture or severe spasticity in the affected upper extremity, as measured by a Modified Ashworth Score ≥ than 3 out of 4.

What they're measuring

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: Baseline

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: 2 weeks

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: 6 weeks

Trial details

NCT IDNCT04977037

SponsorThe University of Texas Health Science Center, Houston

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-02

Results submitted2025-04-01

View on ClinicalTrials.gov More Incomplete Spinal Cord Injury trials

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. diagnosis of a chronic incomplete cervical lesion as defined by the American Spinal Injury Association Impairment scale classification and at least for 6 months post-injury;
✓. upper-extremity weakness associated with tetraplegia with minimal residual thumb and index; finger movement sufficient to grip small objects such as marble;
✓. no brain injury;
✓. no planned alteration in upper-extremity therapy or medication for muscle tone during the course of the study;
✓. no contradiction to tDCS;
✓. access to internet at home.

Exclusion criteria

✕. prior history of seizure;
✕. chronic use of neuroactive medication (e.g., neurostimulants, anticonvulsants, or antidepressants);
✕. any joint contracture or severe spasticity in the affected upper extremity, as measured by a Modified Ashworth Score ≥ than 3 out of 4.

What they're measuring

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: Baseline

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: 2 weeks

Arm and Hand Function as Assessed by Score on the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP)

Timeframe: 6 weeks