This small pilot randomized controlled trial will test whether a brief, web-based intervention inspired by the principles of motivational interviewing helps high-risk men who take pre-exposure prophylaxis (PrEP) moderate their alcohol use, and improve key outcomes of PrEP care, including adherence, persistence, and STI rates. Men with a history of "lapses" in PrEP adherence will be randomly assigned to either (1) use the web-based intervention, called Game Plan for PrEP, or (2) watch video clips encouraging healthy lifestyles (e.g., sleep hygiene, balanced diet; attention-matched control). Participants will complete STI testing and submit dried blood spot (DBS) samples to facilitate analyses of alcohol use and PrEP adherence biomarkers at baseline, 3-months, and 6-months during the study period. Participants will also complete online surveys at baseline, 1-month, 3-months, and 6-months during the study period.
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Pre-exposure Prophylaxis (PrEP) Lapse Days
Timeframe: 6 months
Persistence With Pre-exposure Prophylaxis (PrEP)
Timeframe: Past 6 months
Number of Alcohol Drinking Days
Timeframe: Month 1, Month 3, and Month 6
Average Number of Drinks Consumed Per Drinking Day
Timeframe: Month 1, Month 3, and Month 6
Number of Heavy Drinking Days (5+ Drinks on a Single Occasion)
Timeframe: Month 1, Month 3, and Month 6