TerminatedNot Applicable

Correlation of Peak Tidal Inspiratory Flow Measured Before and After Extubation in Adult Patients With Hypoxemia

Stopped: Difficulty in recruiting patients

United States, Spain5 participantsStarted 2022-04-07

Plain-language summary

In this study, patients who are ready for extubation and indicated for high-flow nasal cannula therapy after extubation will be enrolled, the investigators would measure the patient peak tidal inspiratory flow (PTIF) pre and post extubation to explore the correlation between the two PTIFs. Moreover, different HFNC flows would be applied, to explore the patient response in terms of oxygenation and lung aeration to different flow ratios that matched and are above post-extubation PTIF.

Who can participate

Age range18 Years – 90 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult intubated patients aged between 18 to 90 years * Pass spontaneous breathing trial and receive the order to be extubated * Have at least one of the indications to use HFNC after extubation Exclusion Criteria: * Need to use inhaled epoprostenol via HFNC * Pregnant * Unable to use resuscitation mask, such as facial trauma, claustrophobia * Non-English speaker * Inability to verbally communicate * Using extracorporeal membrane oxygenation (ECMO) * Hemodynamically unstable * Difficult airway

What they're measuring

SpO2/FIO2

Timeframe: 20 minutes after each flow setting

Trial details

NCT IDNCT04971148

SponsorRush University Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-08-08

View on ClinicalTrials.gov More Hypoxemic Respiratory Failure trials