CompletedNot Applicable

A Cross-Sectional Study of Serum Levels of Adipocytokines in Children With Febrile Seizures

Egypt90 participantsStarted 2021-08-23

Plain-language summary

Febrile seizure (FS) is a common neurological condition in children, affecting 2 - 14% of children. FS is defined as seizures occurring in a child aged from six months to five years that is accompanied by a fever (≥38°C) without central nervous system infection. FS is classified into simple febrile seizure (SFS) and complex febrile seizure (CFS). SFS accounts for 70-75% of FS cases and is characterized by being generalized, duration of less than 15 minutes, occurs once in 24 hours, and no previous neurologic problems. We aim to investigate serum levels of adipocytokines, specifically leptin, adiponectin, and IL-6, in children with FS.

Who can participate

Age range6 Months – 6 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age from 6 months to 6 years. * Seizures. * Fever (≥38°C) due to acute infection. * Presented for routine check-up. Exclusion Criteria: * Central nervous system infection. * Epilepsy. * Previous neurological abnormalities. * Inborn errors of metabolism. * Immunological diseases. * Endocrinal diseases (e.g., diabetes mellitus). * Obesity. * Eating disorders. * Gastrointestinal disorders (e.g., diarrhea). * Seizures. * Previous neurological abnormalities * Any illness in the last month

What they're measuring

Serum leptin

Timeframe: within 3 hours of seizures

Serum adiponectin

Timeframe: within 3 hours of seizures

Trial details

NCT IDNCT04967066

SponsorSohag University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-09-23

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