CompletedNot Applicable

Diffusion Weighted Magnetic Resonance Imaging of Brain in Monochorionic Twin Pregnancies With Demise of One Fetus

China60 participantsStarted 2018-01-01

Plain-language summary

Diffusion weighted imaging (DWI) can reflect the microstructure and pathological changes of tissue, and diffusion tensor imaging (DTI) can quantitatively evaluate the fine structure of white matter in brain. In this study, conventional and diffusion-weighted MRI (DWI, DTI) sequences were used to analyze the brain of monochorionic twin pregnancies with demise of one fetus.

Who can participate

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Inclusion criteria

✓. Twin pregnancy was diagnosed and one fetus died in utero
✓. Twin pregnancy with one abnormal fetus
✓. Singleton pregnancy with abnormalities outside the fetal brain

Exclusion criteria

✕. Those who can't cooperate with MRI examination, such as those who have metal, claustrophobia or can't insist on scanning.
✕. Pregnant women with gestational age less than 20 weeks.

What they're measuring

basic information

Timeframe: baseline

basic information

Timeframe: baseline

basic information

Timeframe: baseline

basic information

Timeframe: baseline

basic information

Timeframe: baseline

MRI

Timeframe: baseline

MRI

Timeframe: baseline

MRI

Timeframe: baseline

Trial details

NCT IDNCT04966039

SponsorPeking University Third Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-12-31

View on ClinicalTrials.gov More Twin Pregnancy With Antenatal Problem trials