CompletedNot Applicable

Dyadic Neurofeedback for Emotion Regulation in Youth With Maternal Adversity

United States30 participantsStarted 2021-05-11

Plain-language summary

This study will examine the effect of a real-time functional magnetic resonance imaging (fMRI) dyadic neurofeedback protocol with mothers and their adolescent daughters. Mothers will view a moving bar showing their daughters' brain activity on a computer screen while talking to their daughters.

Who can participate

Age range14 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: All participants inclusion criteria: * Biological female * Sufficient English fluency to complete tasks * Co-residing at least 4 days per week Inclusion criteria for adult participants: * Primary caregiver for more than 50% of child's lifespan * History of at least two adverse childhood experiences * Biological parent of adolescent participant Inclusion criteria for adolescents: * Eligible for fMRI * Right-handed * Body mass index between 16 and 40 (inclusive) * Age 14-17 years Exclusion Criteria: Exclusion criteria for all participants: * Current psychiatric diagnosis Exclusion criteria for adolescent participants: * Neurodevelopmental delay * History of psychiatric disorder * Medications influencing fMRI * Medical conditions influencing fMRI

What they're measuring

Blood Oxygen Level-Dependent (BOLD) signal changes (brain activation)

Timeframe: One hour (measured during first scan session)

Blood Oxygen Level-Dependent (BOLD) signal changes (brain activation)

Timeframe: One hour (measured during second scan session)

Resting-state network activity (change over time)

Timeframe: Change in resting-state activity over one week, from Session 1 to Session 2. Resting-state scan will last approximately 8 minutes.

Parent validating statements (change over time)

Timeframe: Change in frequency in validation as coded by the manual over one week, from Session 1 to Session 2. Validating statements are measured and recorded during the scan sessions.

Trial details

NCT IDNCT04964726

SponsorOklahoma State University Center for Health Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-12-07

View on ClinicalTrials.gov More Emotional Dysfunction trials

Who can participate

Age range14 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Blood Oxygen Level-Dependent (BOLD) signal changes (brain activation)

Timeframe: One hour (measured during first scan session)

Blood Oxygen Level-Dependent (BOLD) signal changes (brain activation)

Timeframe: One hour (measured during second scan session)

Resting-state network activity (change over time)

Timeframe: Change in resting-state activity over one week, from Session 1 to Session 2. Resting-state scan will last approximately 8 minutes.

Parent validating statements (change over time)

Timeframe: Change in frequency in validation as coded by the manual over one week, from Session 1 to Session 2. Validating statements are measured and recorded during the scan sessions.