Endometrial Compaction in Assissted Reproduction (NCT04962789) | Clinical Trial Compass
UnknownNot Applicable
Endometrial Compaction in Assissted Reproduction
Egypt145 participantsStarted 2021-08-20
Plain-language summary
To record the dynamic change of endometrial thickness (Day of embryo transfer Versus. Day of ovulation trigger administration in case of fresh cycles or end of estrogen phase in frozen cycles), and to investigate the impact of endometrial thickness change on pregnancy outcomes
Who can participate
Age range
18 Years – 40 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* • Infertile women aged 18 years to 40 years undergoing IVF/ ICSI for any indication.
Exclusion Criteria:
* • History of recurrent pregnancy loss (≥ 2 spontaneous abortions) and/or history of recurrent (≥ 2) ICSI failure after embryo transfer.
* Uterine malformations.
* Uncorrected hydrosalpinx.
* Intrauterine conditions affecting pregnancy outcomes such as ( intrauterine adhesions, fibroids, polyps).
* Any previous hysteroscopic surgery eg. Metroplasty or hysteroscopic myomectomy or uterine surgeries involving the endometrium eg. myomectomy during which uterine cavity was opened.
* History suggesting endometritis.
* Use of hCG for endometrial preparation or luteal phase support.
* Poor quality embryos( according to Istanbul consensus workshop on embryo assessment )
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is looking at something called 'endometrial compaction' — can you explain what that means and whether the thickness or changes in my uterine lining have been a factor in my fertility treatments so far?
2The trial's recruitment status is listed as unknown, so can you find out whether this study is still actively enrolling patients, and if not, whether there are similar studies I could consider?
3Since this is a phase 'NA' trial focused on measuring ongoing pregnancy rates, what does that tell us about how much is already known about this approach, and how would participating affect the decisions we make about my current treatment plan?
4How does looking at endometrial compaction fit into what my care team already does to assess my uterine lining before a transfer, and would joining this trial change anything about my standard monitoring or protocols?
5If I'm not a good fit for this trial or it's no longer enrolling, are there other evidence-based options we should be discussing to address any concerns about my endometrial lining and its role in improving my chances of a successful pregnancy?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Ongoing pregnancy rate
Timeframe: 12 weeks after embryo transfer if hCG tested positive