Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorect… (NCT04955808) | Clinical Trial Compass
SuspendedNot Applicable
Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery
Stopped: Due to slow accrual on this trial, we will allow sites time to work on close-out procedures and filling out necessary paperwork before taking the steps to forma
United States2,400 participantsStarted 2017-02-07
Plain-language summary
This research trial studies how well biospecimen collection works in identifying genetic changes in patients with breast, prostate, colorectal, liver, or kidney cancer or multiple myeloma undergoing surgery. Studying samples collected during surgery may add to the understanding of cancer by looking for the genetic changes that cause early cancer onset in people of certain racial and ethnic groups.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with either:
* Histologically confirmed invasive carcinoma or multiple myeloma OR
* Clinical diagnosis of carcinoma or multiple myeloma OR
* Suspected clinical diagnosis of multiple myeloma
* Patients with one of following tumor types and age ranges:
* Breast cancer diagnosis at ages 18-45
* Colon cancer diagnosis at ages 18-55
* Kidney cancer at diagnosis at ages 18-50 (American Indian or Alaska Native \[AIAN\] and non-Hispanic Whites \[NHW\] only)
* Liver cancer diagnosis at ages 18-55
* Prostate cancer diagnosis at ages 18-55
* Multiple myeloma diagnosis at ages 18-50
* Patients whose tumor specimen was collected or will be collected during one of the following routine procedures:
* Surgery to remove cancer OR
* Routine biopsy procedures performed to confirm a histologic diagnosis OR
* Routine biopsy procedure performed to obtain additional tumor material for routine prognostic or predictive biomarkers OR
* Routine procedure to place a vascular access device prior for systemic therapy
* Patients who have received no therapy for their cancer other than surgery, irrespective of stage
* Collection of specimens from living patients:
* Ability to understand and willingness to sign a written informed consent document indicating their willingness to have their tissue or biologic fluid specimens used for research as outlined in this protocol
* Collection of specimens from deceased patients:
* Banked tissue samples …
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Acquisition of tissue, blood, and other biospecimens for research purposes