CompletedNot Applicable

Association of Processing Speed Dysfunction and Brain Functional Abnormality in ECTS

China68 participantsStarted 2019-06-01

Plain-language summary

Epilepsy with centrotemporal spikes (ECTS) is the most common epilepsy syndrome in children. Language impairment has been widely investigated in patients with ECTS, but little is known about the cognitive dysfunction of processing speed and its neuroimaging mechanism.

Who can participate

Age range6 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * (a) age between 6 and 18 years; (b) 18F-FDG PET examination more than 48 h since the last seizure, (c) no structural abnormalities associated with epilepsy detected on routine MRI Exclusion Criteria: * (a) any history of other neurological or psychiatric disorders; (b) pre-scan plasma glucose level \> 120 mg/dl before 18F-FDG PET/CT examination;(c) any contraindications for MRI examination ; (d) head movement (translation \> 3 mm or rotation \> 3 degree ) during MRI examination

What they're measuring

Processing speed index

Timeframe: Through study completion, about 2 years

Standardized uptake value ratio

Timeframe: Through study completion, about 2 years

Functional connectivity

Timeframe: Through study completion, about 2 years

Trial details

NCT IDNCT04954729

SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-06-01

View on ClinicalTrials.gov More Epilepsy, Rolandic trials