UnknownNot Applicable

The Circadian Rhythm of ICU Patients With Acute Myocardial Infraction and the Effect of Light Therapy

Taiwan70 participantsStarted 2021-05-12

Plain-language summary

By using subjective and objective measurements, the investigators monitor the change of circadian rhythm in Intensive Care Unit (ICU) patients with acute myocardial infarction and the effect of light therapy.

Who can participate

Age range

35 Years – 85 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis for admission is acute myocardial infarction with severity between Killip I-III. * Age is between 35-85. * Participants who are willing to participate in the study and sign the informed consent. Exclusion Criteria: * Using sedative hypnotic drugs. * Blindness or severe cataract. * Neurological diseases such as epilepsy, brain injury, or stroke. * Severe mental disorder such as major depressive disorder, bipolar disorder, schizophrenia, intellectual disability or substance use disorders. * Unable to communicate. * Participants who are unwilling to participate in the study or refuse to sign the informed consent. * Participants who are not suitable to include in this study, evaluate by PI or Co-PI.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Changes of the circadian rhythm during admission by actigraphy

Timeframe: an average of 2 weeks of continuous monitoring since baseline till discharge, up to 4 weeks

Changes of the circadian rhythm during admission by heart-rate-variation-analysis

Timeframe: baseline for 48hours, and 24hours before discharge

Changes of Melatonin level

Timeframe: collect saliva in the morning and at the night of Day 1 and the day of discharge

Changes of Vitamin D level

Timeframe: blood sampling at Day 1 and the day of discharge

Trial details

NCT IDNCT04953767

SponsorChang Gung Memorial Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-31

Contact for this trial

Wei-Chih Chin

+886 3 3281200 auaug0327@cgmh.org.tw

View on ClinicalTrials.gov More Circadian Dysrhythmia trials