CompletedNot Applicable

Mental Health Associations With Vitiligo

United Kingdom36,104 participantsStarted 2021-06-18

Plain-language summary

This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with vitiligo compared to controls and to evaluate whether the relative risks may vary by different ethnicity.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All eligible adults ≥18 (as at date of vitiligo diagnosis for cases or start of follow-up for controls) registered with GP practices contributing data to OPCRD between January 1, 2004 and December 31, 2020, were eligible for inclusion in the study. Exclusion Criteria: * People with less than 1 year of follow up available

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Number of Participants With Depressive Episodes

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Risk of Depressive Episodes Within Adult Patients With Vitiligo

Timeframe: Within two years of vitiligo diagnosis. For matched controls, within two years of the date of diagnosis of their matched case.

Number of Participants With Anxiety Disorder

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Number of Participants With Recurrent Depressive Disorder

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Risk of Anxiety Disorder Within Adult Patients With Vitiligo

Timeframe: Within two years of vitiligo diagnosis. For matched controls, within two years of the date of diagnosis of their matched case.

Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo

Trial details

NCT IDNCT04953338

SponsorMomentum Data

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2022-08-30

Results submitted2025-05-28

View on ClinicalTrials.gov More Vitiligo trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Number of Participants With Depressive Episodes

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Risk of Depressive Episodes Within Adult Patients With Vitiligo

Timeframe: Within two years of vitiligo diagnosis. For matched controls, within two years of the date of diagnosis of their matched case.

Number of Participants With Anxiety Disorder

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Number of Participants With Recurrent Depressive Disorder

Timeframe: At the time of diagnosis in all people diagnosed with vitiligo 2004-2020 inclusive. For matched controls, the date of diagnosis of their matched case.

Risk of Anxiety Disorder Within Adult Patients With Vitiligo

Timeframe: Within two years of vitiligo diagnosis. For matched controls, within two years of the date of diagnosis of their matched case.

Risk of Recurrent Depressive Disorder Within Adult Patients With Vitilgo