An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.

Inclusion Criteria: * Man or woman ≥18 years old. * Written informed consent obtained from the patient prior to performance of any study-specific procedure. * History of at least one episode of HSV-2 genital herpes lesions in the 12 months preceding the screening, and seropositive for HSV-2 as determined by Western blot OR PCR-positive for HSV-2 (newly diagnosed patients). * Patients who are medically stable in the opinion of the investigator. * Patients who, in the opinion of the investigator, are able to understand and comply with the study requirements (attend regular telephone calls/study site visits/home visits/self-completion of questionnaires, self-swabbing). * Seronegative for HIV, as determined by laboratory testing. Patients documented to be positive to HIV will not be eligible for study participation Exclusion Criteria: * Prior receipt of a vaccine or candidate vaccine containing HSV antigens. * Immunocompromised patients, as per medical history and investigator judgement. * Other genital tract disorders or sexually transmitted diseases that may interfere with the assessment of the study (as per investigator's judgement).