UnknownNot Applicable

Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment

China484 participantsStarted 2021-04-14

Plain-language summary

Encephalitis and meningitis are serious central nervous system diseases. There is currently a lack of comprehensive and accurate diagnosis and treatment pathways. Therefore, we conducted this multicenter, prospective, and randomized controlled study. It was designed to evaluate the diagnostic performance and its impact on the outcomes of the patients enrolled. As such, we came to the results of the optimal process of diagnosis and treatment strategy of encephalitis/meningeal syndromes with improved effective treatments.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Stiff neck
✓. Change in state of consciousness
✓. Other signs of meningitis: such as meningeal irritation.
✓. Fever during the course of the disease (≥ 38℃); (oral temperature)
✓. Convulsions or focal neurological symptoms;
✓. Increase in the number of cerebrospinal fluid cells (\>4\*10\^6/L);
✓. Abnormal EEG that meets the manifestations of encephalitis and cannot be attributed to other reasons
✓. Imaging suggests encephalitis (CT or MRI)

What they're measuring

The change Modified Rankin Scale (mRS) at 1 year

Timeframe: mRS should be measured at 1 year

Trial details

NCT IDNCT04946682

SponsorWen-hong Zhang

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-04-14

View on ClinicalTrials.gov More Encephalitis trials