UnknownNot Applicable

Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms

China40 participantsStarted 2021-07-01

Plain-language summary

This study was designed to whether there is a measurable reduction in inflammation in walls of unruptured vertebrobasilar dissecting aneurysms with atorvastatin.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Be aged 18 or over, male or non-pregnant female;
. Patients have a unruptured vertebrobasilar dissecting aneurysm identified on imaging (CT, MRI or DSA)
. Patients with wall enhancement and intramural hematomas of UVBDAs by HR-VW-MRI before treatment.
. Patients who is able to understand the objective of the trail, agrees and signs the written informed consent form.

Exclusion criteria

. The aneurysm types of non-dissecting aneurysm, such as saccular aneurysms, fusiform aneurysms and traumatic aneurysms, etc.;
. Patients with MRI contraindications: metallic implant, contrast allergy, claustrophobia, etc.;
. Planned treatment of the aneurysm within 6 months;
. Several impaired liver or renal functions;
. Retreatment of recurrent aneurysm;
. Pregnant or lactating women;
. Patients with malignant diseases, such as liver disease, kidney diseases, congestive heart failure, malignant tumors, etc.;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

1.Change of aneurysm wall inflammation as measured by HR-VW-MRI.

Timeframe: 6 months

Trial details

NCT IDNCT04943783

SponsorBeijing Neurosurgical Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-01

Contact for this trial

Mirzat Turhon, MD

+8618699158800 18699158800@163.com

View on ClinicalTrials.gov More Dissecting Aneurysm of Cerebral Artery trials