Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment. In spite of successful treatment of the infection, long-term cognitive problems or mental fatigue may ensue. The reason for this dysfunction may be a continuing inflammatory state or damage to brain tissue caused by the abscess. The investigators will evaluate these possibilities with the use of \[18F\]deoxyglucose-positron emission tomography (FDG-PET) and electroencephalography (EEG) in patients who have been treated for brain abscess and who experience cognitive problems and/or fatigue. FDG-PET may identify both inflammation and altered neuronal activity (the latter indicating damage to brain tissue), and EEG may identify altered neuronal activity, including changes in neuronal network activity.
Age range
16 Years
Sex
ALL
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A change in FDG-PET signal indicating inflammation
Timeframe: When all patients have been followed up for at least 1 year.
A change in FDG-PET signal indicating a change in neuronal activity
Timeframe: When all patients have been followed up for at least 1 year.
A change in EEG activity indicating a change in neuronal activity based on EEG power in alpha, theta, and delta frequencies.
Timeframe: When all patients have been followed up for at least 1 year.