RecruitingNot Applicable

PRP Versus HA IN OSTEOARTHRITIS OF THE PATELLOFEMORAL JOINT

Italy166 participantsStarted 2022-10-26

Plain-language summary

The aim of the study is to compare the 12-month clinical outcomes of patients with patellofemoral osteoarthritis undergoing infiltrative treatment with fresh PRP and HA

Who can participate

Age range30 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age between 30 and 65;
✓. Signs and symptoms of isolated patellofemoral osteoarthritis present in one or both knees;
✓. Radiographic signs of isolated patellofemoral osteoarthritis (according to Iwano et al stage 1-3 classification) or chondropathy (assessed on MRI) with K-L grade of the other compartments ≤ 2. \[PMID: 2302884 - PMID: 27979409\] ;
✓. Hemoglobin \> 11 g/dl; Platelet count \> 150,000 plt/mm3 (Recently performed CBC exam);
✓. No clinically significant electrocardiographic alterations (Recently performed ECG).
✓. Ability and consent of patients to actively participate in clinical follow-up;
✓. Signature of informed consent.

Exclusion criteria

✕. Patients unable to express consent;
✕. Patients who have undergone intra-articular infiltration of another substance within the previous 6 months;
✕. Patients undergoing knee surgery within the previous 12 months;
✕. Patients with malignant neoplasms;
✕. Patients with rheumatic diseases;
✕. Patients with diabetes;
✕. Patients with hematologic diseases (coagulopathies);
✕. Patients on anticoagulant-antiaggregant therapy;

What they're measuring

KOOS-Pain Score

Timeframe: 12 months

Trial details

NCT IDNCT04937998

SponsorIstituto Ortopedico Rizzoli

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09

Contact for this trial

Roberta Licciardi, MSc

0516366567 roberta.licciardi@ior.it

View on ClinicalTrials.gov More Patellofemoral Osteoarthritis trials