CompletedNot Applicable

Study on the Effect of Capacity Shock Intervention Under Goal-directed Hemodynamic Management on P-V Loop

China20 participantsStarted 2020-06-01

Plain-language summary

By observing the changes of P-V loop in capacity shock intervention Under Goal-directed Hemodynamic Management in patients undergoing total knee replacement, we investigate the effect of capacity shock on cardiac contractility and work in order to seek a more effective target plan of capacity shock for intraoperative patients.

Who can participate

Age range40 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: ASAI-II age 40- 70 weight 48 - 72 kg. Exclusion Criteria: Body mass index \>30 or \<15 kg/m2 Valve heart disease Left ventricular ejection fraction (LVEF) is less than 50% History of lung disease Preoperative arrhythmic disorder Permanent pacemaker Need for mechanical heart Support, Severe extrinsic vascular disease Valve dysfunction OED monitoring probe insertion contraindications Patients with preoperative assessments

What they're measuring

Ees

Timeframe: Baseline，After induction

Ees

Timeframe: Immediately after the intervention,complete of the first round of the fluid challenge

Ees

Timeframe: Immediately after the intervention,complete of the second round of the fluid challenge

Ees

Timeframe: 1h after the first fluid challenge

Ees

Timeframe: At the end of surgery

Timeframe: Baseline，after induction

Timeframe: Immediately after the intervention,complete of the first round of the fluid challenge

Timeframe: Immediately after the intervention,complete of the second round of the fluid challenge

Trial details

NCT IDNCT04934761

SponsorGuangzhou Red Cross Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-05-01

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