Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs (NCT04930289) | Clinical Trial Compass
By InvitationNot Applicable
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
United States, Belgium2,000 participantsStarted 2021-10-15
Plain-language summary
The objective of this registry is to collect and evaluate various clinical effectiveness parameters in patients with transplanted donor lung that were preserved and transported within the LUNGguard system, as well as retrospective standard of care patients
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Donor and donor lungs matched to the prospective recipient based upon institutional medical practice
* Registered male or female primary lung transplant candidates including pediatric candidates
Exclusion Criteria:
* Donor and donor lungs that do not meet institutional clinical requirements for transplantation
* Patients who are incarcerated persons (prisoners)
* Patients who have had a previous major organ transplant (heart, lungs, liver, kidney, pancreas)
* Patients who are receiving multiple organ transplants
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of subjects with Primary Graft Dysfunction (PGD)
Timeframe: Post-transplant through 1 year post
2
Number of subjects with rejection
Timeframe: Post-transplant through 1 year post
3
Survival
Timeframe: Post-transplant through 1 year post
4
ICU Length of Stay
Timeframe: Transplant through 1 year post-transplant
5
Hospital Length of Stay
Timeframe: Transplant through 1 year post-transplant