WithdrawnNot Applicable

Blood Components Changes by Using of Ringer's Lactated as Detergent In Autologous Blood Cell Transfusion

Stopped: halted by the pandemic of COVID-19

China0Started 2021-10

Plain-language summary

Placenta accreta spectrum (PAS) disorders are associated with increased maternal morbidity and mortality related to life-threatening hemorrhage, and greater potential need for blood transfusion. Clinical evidences have confirmed that the use of autologous blood cell transfusion is safe and effective for patients with obstetric haemorrhage. Normal saline is the solution recommended for red cell washing, administration and salvage. However, there is growing concern that normal saline is more toxic than balanced, buffered crystalloids such as Lactated Ringer's and Plasma-Lyte. The purpose of this study is to evaluate the blood components using of Ringer's Lactated by a prospective, single-center, open, and single-arm clinical trial.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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Inclusion Criteria: * Between 18 and 45 years old * Without health problem nor disease requiring regular medical treatment Exclusion Criteria: * subject with contraindication for drawing blood * Subject with physical or mental disability or restriction of liberty that would prevent autotransfusion

What they're measuring

Change in hematological parameters

Timeframe: Baseline (Day 1), until 2 days after autotransfusion

Change in hematological parameters

Timeframe: Baseline (Day 1), until 2 days after autotransfusion

Change in hematological parameters

Timeframe: Baseline (Day 1), until 2 days after autotransfusion

Trial details

NCT IDNCT04927988

SponsorMaternal and Child Health Hospital of Foshan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-09

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