Not Yet RecruitingNot Applicable

Neurological Sequelae in Patients With Acute Carbon Monoxide Poisoning

China1,250 participantsStarted 2021-08-01

Plain-language summary

The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.

Who can participate

Age range16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients present within 12 hours after acute carbon monoxide poisoning; * age older than 16 years. Exclusion Criteria: * pregnant women； * patients receive oxygen therapy before presentation; * have history of acute carbon monoxide poisoning within 1 year; * have been diagnosed any of the following disease: Parkinson disease; cognitive disorder, psychiatric disorders, sequelae of cerebral infarction or hemorrhage, chronic kidney disease and receive hemodialysis, congestive heart failure ( NYHA class III-IV)

What they're measuring

Changes of Mini-mental State Examination (MMSE) score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks

Changes of Mini-mental State Examination (MMSE) score at 6 months

Timeframe: Changes of score from baseline to 6 months

Changes of Mini-mental State Examination (MMSE) score at 12 months

Timeframe: Changes of score from baseline to 12 months

Changes of Montreal cognitive assessment (MoCA）score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks

Changes of Montreal cognitive assessment (MoCA）score at 6 months

Timeframe: Changes of score from baseline to 6 months

Changes of Montreal cognitive assessment (MoCA）score at 12 months

Timeframe: Changes of score from baseline to 12 months

Changes of Hamilton Depression Scale(HAMD) score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks

Trial details

NCT IDNCT04925297

SponsorThe First Hospital of Jilin University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-05-01

Contact for this trial

Ning Dong, M.D.

+8615804301769 dnjl2007@jlu.edu.cn

View on ClinicalTrials.gov More Carbon Monoxide Poisoning trials

Who can participate

Age range16 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Changes of Mini-mental State Examination (MMSE) score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks

Changes of Mini-mental State Examination (MMSE) score at 6 months

Timeframe: Changes of score from baseline to 6 months

Changes of Mini-mental State Examination (MMSE) score at 12 months

Timeframe: Changes of score from baseline to 12 months

Changes of Montreal cognitive assessment (MoCA）score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks

Changes of Montreal cognitive assessment (MoCA）score at 6 months

Timeframe: Changes of score from baseline to 6 months

Changes of Montreal cognitive assessment (MoCA）score at 12 months

Timeframe: Changes of score from baseline to 12 months

Changes of Hamilton Depression Scale(HAMD) score at 6 weeks

Timeframe: Changes of score from baseline to 6 weeks