CompletedNot Applicable

Transcranial Magnetic Stimulation For Visual Snow Syndrome

United States10 participantsStarted 2019-08-01

Plain-language summary

This study aims to investigate the feasibility of the use of repetitive transcranial magnetic stimulation (rTMS) for symptoms associated with Visual Snow syndrome (VS).

Who can participate

Age range

19 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * A diagnosis of VS that meets International Headache Society criteria * Able to provide meaningful informed consent * Visual snow must be present for more than three months and must be persistent (i.e. continuous) * A prior clinical Brain MRI with and without contrast done in the past 3 years that does not show signs of clinically significant brain lesions (no evidence of multiple sclerosis, stroke, brain tumor, cortical heterotopia or other cortical developmental abnormalities, arteriovenous malformation, etc…) Exclusion Criteria: * Syndrome meeting criteria for Hallucinogen-persisting perception disorder * Prior treatment with TMS for any disorder * Epilepsy, family history of epilepsy, or personal history of seizure * Any medical condition or medication that increases the risk of seizure * Pacemaker or other implantable medical device * Metal in the skull, not including the mouth * Unstable cardiac, pulmonary, or other systemic illness * Pregnancy * Bipolar disorder * History of suicidality

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

TMS Side Effect Questionnaire

Timeframe: Week 1

TMS Side Effect Questionnaire

Timeframe: Week 2

TMS Side Effect Questionnaire

Timeframe: Month 1

TMS Side Effect Questionnaire

Timeframe: Month 3

Visual Noise Task

Timeframe: Week 1

Visual Noise Task

Timeframe: Week 2

Visual Noise Task

Timeframe: Month 1

Visual Noise Task

Timeframe: Month 3

Trial details

NCT IDNCT04925232

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-11-30

View on ClinicalTrials.gov More Visual Snow Syndrome trials

Who can participate

Age range

19 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

TMS Side Effect Questionnaire

Timeframe: Week 1

TMS Side Effect Questionnaire

Timeframe: Week 2

TMS Side Effect Questionnaire

Timeframe: Month 1

TMS Side Effect Questionnaire

Timeframe: Month 3

Visual Noise Task

Timeframe: Week 1

Visual Noise Task

Timeframe: Week 2

Visual Noise Task

Timeframe: Month 1

Visual Noise Task

Timeframe: Month 3