Prevalence of Acute Hepatic Porphyria (NCT04923516) | Clinical Trial Compass
CompletedNot Applicable
Prevalence of Acute Hepatic Porphyria
France150 participantsStarted 2021-08-23
Plain-language summary
To determine the proportion of patients suffering from acute hepatic porphyria (AHP) from different hospital departments and referred to an internist referent for a suggestive clinical picture with a first negative etiological assessment.
Who can participate
Age range18 Years – 60 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Man or woman aged 18 to 60;
* Presenting severe abdominal pain, afebrile and diffuse over several days, evolving for less than 5 years;
* With at least one of the following symptoms:
* Peripheral neurological symptoms: decreased driving force and pain in the limbs (roots of the thighs), etc. ;
* Central neurological symptoms: psychiatric (depression, anxiety, insomnia), disturbances of consciousness, etc. ;
* Autonomous neurological symptoms: tachycardia, nausea, vomiting, constipation, etc.
* With a first negative etiological assessment requested by an emergency physician, gastroenterologist, gynecologist, neurologist, internist or another specialty, or with a diagnosis of acute hepatic porphyria less than 6 months;
* Patient able to understand the information related to the study and having indicated his non-objection to the collection of data concerning him;
Exclusion Criteria:
* Patient with a diagnosis of acute hepatic porphyria for more than 6 months;
* Patient unfit to participate in the study, due to cognitive or linguistic difficulties;
* Protected patient (under legal protection, or deprived of liberty by judicial or administrative decision).
What they're measuring
1
Binary criterion corresponding to the diagnosis of acute hepatic porphyria (acute hepatic porphyria + / acute hepatic porphyria -) via physiological parameter.
Timeframe: 1 day
Trial details
NCT IDNCT04923516
SponsorAssociation pour la Recherche en Medecine Interne