Many studies have attempted to find the predictors of adverse neonatal outcome in women with Intrahepatic Cholestasis of Pregnancy(ICP).Serum total bile acid level exceeding 40 µmol/L has been associated with increased risk of meconium staining, low Apgar scores, preterm delivery, and stillbirth.Other predictors such as level of transaminases, history of cholelithiasis, and hepatitis virus infection have been studied but the results are inconclusive.A more comprehensive investigation involving multiple neonatal outcomes and a wide variety of outcome predictors is needed in order to establish guidelines for optimal timing of delivery in pregnancies complicated by ICP. The aim of our study was to evaluate wide variety of predictors of adverse neonatal outcomes in a large cohort of women with ICP .
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Hypoglycemia
Timeframe: up to 28 days
Hyperbilirubinemia
Timeframe: up to 28 days
NICU admission
Timeframe: up to 28 days
RDS
Timeframe: up to 28 days
TTN
Timeframe: up to 28 days
mechanical ventilation use
Timeframe: up to 28 days
oxygen by nasal cannula
Timeframe: up to 28 days
pneumonia
Timeframe: up to 28 days
stillbirth
Timeframe: up to 1 day